1.         Childhood obesity and Insulin resistance

2.         Fat cell development and function

Selected Publications:

1.         Lu X, Ji C, Xu H, Li X, Ding H, Ye M, Zhu Z, Ding D, Jiang X, Ding X, Guo X. Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress. Int J Pharm. 2009, 375 (1-2):89-96. 

2.         Ye K, Ji CB, Lu XW, Ni YH, Gao CL, Chen XH, Zhao YP, Gu GX, Guo XR. Resveratrol attenuates radiation damage in Caenorhabditis elegans by preventing oxidative stress. J Radiat Res (Tokyo). 2010, 51 (4):473-479. 

3.         Ji C, Chen X, Gao C, Jiao L, Wang J, Xu G, Fu H, Guo X, Zhao Y, IL-6 induces lipolysis and mitochondrial dysfunction, but does not affect insulin sensitivity in 3T3-L1 adipocytes. J Bioenerg Biomembr. 2011, 43:367-375.

4.         Ji C, Guo W, Zhang M, Lu X, Ni Y, Guo X. Caenorhabditis elegans ucp-4 regulates fat metabolism: Suppression of ucp-4 expression induced obese phenotype and caused impairment of insulin like pathway. Gene. 2012,491:158-164.

5.         Ni Y, Ji C, Wang B, Qiu J, Wang J, Guo X. A Novel pro-adipogenesis actor abundant in adipose tissues and over-expressed in obesity acts upstream of PPARγ and C/EBPα. J Bioenerg Biomembr. 2013, 45(3):219-228.

6.         Wan J, Cui XW, Zhang J, Fu ZY, Guo XR, Sun LZ, Ji CB. Peptidome analysis of human skim milk in term and preterm milk. Biochem Biophys Res Commun. 2013, 438(1):236-241.

7.         Zhang J, Cui X, Shen Y, Pang L, Zhang A, Fu Z, Chen J, Guo X, Gan W, Ji C. Distinct expression profiles of LncRNAs between brown adipose tissue and skeletal muscle. Biochem Biophys Res Commun. 2014 Jan 17;443(3):1028-34.

8.         Shi C, Zhu L, Chen X, Gu N, Chen L, Zhu L, Yang L, Pang L, Guo X, Ji C, Zhang C. IL-6 and TNF-α Induced Obesity-Related Inflammatory Response Through Transcriptional Regulation of miR-146b. J Interferon Cytokine Res. 2014 Jan 15. [Epub ahead of print]

9.         Chen L, Wu JJ, Chen XH, Cao L, Wu Y, Zhu LJ, Lv KT, Ji CB, Guo XR. Measurement of Fetal Abdominal and Subscapular Subcutaneous Tissue Thickness during Pregnancy to Predict Macrosomia: A Pilot Study. PLoS One. 2014 Mar 27;9(3):e93077.