1、Technical Name：Neonatal screening

2、Technical Introduction：Neonatal screening is a general investigation for every newborn by advanced experimental techniques. Namely, every newborn with fully breast-feeding in 72 hours and subsequent time after birth is collected his/her heel blood by dropping on filter paper. The biological specimens are stored at the low temperature environment of 4 degree and detected by the newborn screening center with regular delivery. The positive children will be treated timely by the specialists and a lone-term follow-up after diagnosis.

3、Current Situation And Achievements：Our Center was launched firstly the newborn screening project in Jiangsu province in 1985, mainly including three diseases: hyperphenylalaninemia (HPA), congenital hypothyroidism (CH), and congenital adrenal hyperplasia (CAH). After acceptance and evaluation by Jiangsu Province Health Department in 2002, our center is now a quality control center of neonatal screening and a branch chairman unit in neonatal screening of Jiangsu province association of improving birth of outcome and child development. Taken Nanjing maternity and child health care hospital as a core, our center is radiated in various confinements in the whole city with the coverage of 100% and the screening rate of over 98%. The tandem mass spectrometry newborn screening program was carried out at the end of 2013, expanding newborn diseases screening to 29 species.

4、Future Outlook：The tandem mass spectrometry newborn screening program will be promoted to the whole city, and urinary gas chromatography/mass spectrometry and gene diagnosis of inherited metabolic diseases will be established gradually. A complete system, involving newborn screening for inherited metabolic disease, diagnosis and treatment (including genetic diagnosis and classification) and prenatal diagnosis, will be established.